You run for cover but you can't escape the 2nd attack

from The Killers – Miss Atomic Bomb Lyrics on Rap Genius

Meaning

Flowers is making an allusion to the dropping of the atomic bomb on Nagasaki at the end of World War II. The reference serves to draw a parallel between the atomic bomb tests that were conducted in the Nevada desert in the 1940s and a relationship destroyed by two great mistakes. There’s nothing more terrifying than hearing that air raid siren and knowing that in the next instant you’ll be wiped from existence. That single moment must feel like a lifetime, much like how the fallout of a single mistake will play out in slow motion before your eyes.

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