Do what you want with me
What you want with my body
Do what you want with me
What you want with my body, girl

from Lady Gaga (Ft. R. Kelly) – Do What U Want Lyrics on Rap Genius

Meaning

This is Gaga proclaiming that “You can praise me, hate me, adore me, or threaten me, but nothing will bring me down.” She is also addressing all the hate she’s been receiving, including her comparisons to Madonna and Katy Perry. She responds to this hate here and says she’s fine receiving all the hate because they’re not bringing her down. She uses this body metaphor as an image to the public, as it’s worth much less than her internals (her mind and voice). Like she said in one of her previous tweets, “i don’t need anybodys permission to be remembered. I will be. Whether they like it or not.”

https://twitter.com/ladygaga/statuses/392000563325329408

https://twitter.com/ladygaga/statuses/391999414446735360

It could also be a statement how the media was only focused on her butt rather more than her performance and vocals when she performed at the VMAs. They obviously care about her body than her true inner self, so Gaga lets them do anything with it.

This could be referencing her past as a stripper when she was performing in New York night clubs.

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